Carbomer Alternative. The gel produces fine transparent film on your eye. BACKGROUND Ca

The gel produces fine transparent film on your eye. BACKGROUND Carbomers are a group of polymers composed of acrylic acid. Introduction Derby and Derbyshire Integrated Care Board (DDICB) currently spends approximately £1m on prescribing for dry eye preparations. Sep 6, 2024 · The Poly-Gel brand of carbomer 0. Helping you to replace carbomer’s unique velvety texture easily! Jul 1, 2022 · Carbomers are versatile and stable rheology modifiers but are synthetic and cannot be formulated in a natural-claimed product. Skin care: It is an excellent emulsifier that prevents water and oil from separating in skincare products. This product is perfect for a diverse range of personal care Jan 15, 2024 · Carbomer, on the other hand, is an experimentally crafted synthetic polymer that is commonly used as a thickener in various personal care products such as gels and lotions. Sep 10, 2024 · Our comprehensive guide to cosmetic ingredients to avoid helps you find and purchase safe, healthy products for you and your family. This means their viscosity decreases under shear stress. communications@nhs. What are the side effects of Carbomer? Carbomer is generally considered safe and well-tolerated when used as intended in cosmetic and pharmaceutical formulations. . Nov 20, 2018 · What is it? A water soluble thickening agent that creates beautiful crystal clear gels without the tacky skin feel of other gums. We developed an instrumental protocol based on rheology and texture analysis to evaluate alternatives to Cost-effective Switching Guidance: Ocular Lubricants prescribed for regular use for Chronic Dry Eye conditions as per the Dry Eye Pathway for Tear Film Disorder in Primary Care Carbomer is a synthetic solid polymer defined as a microplastic by the European microplastic restriction. It’s funny, I’ve been cooking with some of these gums for years, but it never once occurred to me to smear any of them on my face! Nov 24, 2025 · Learn what is a substitute for carbomer, from natural gums like xanthan gum to cellulose derivatives and synthetic options, for pharmaceutical and cosmetic applications. Recommendations and Mar 31, 2023 · Wenn in der Rezeptur Gele oder hochviskose Lösungen hergestellt werden sollen, stellt sich oft die Frage, wie am besten mit dem Gelbildner verfahren werden soll: Aufstreuen oder doch lieber 4 days ago · Additionally, the increasing shift towards natural and organic ingredients presents a challenge for synthetic carbomers, prompting the industry to explore bio-based alternatives. Jul 15, 2024 · Cancer has been an enormous pain point for patients and regulatory bodies across the globe. The synthetic polymers S1 (carbomer) and S2 (sodium polyacrylate) are positively loaded on both F1 and F2. This proposal was in response to the current product, Poly-Gel, being discontinued by its supplier. Many formulations contain carbomer, or relatives of carbomer, based on polymers of acrylic acid. They are widely used as inactive ingredients in drug products as fillers, emulsifiers, gelling agents, and binding agents. Chemlink are pleased to introduce a high-efficacy alternative to carbomers which require no neutrilisation, simply add to water! Consistent Performance Manufactured under GMP conditions, Motusflex® polymers make ideal rheology modifiers for topical pharmaceutical applications 1 day ago · The Benzene Free Carbomer market has emerged as a significant segment within the broader chemical and cosmetic ingredients industry, driven by increasing consumer awareness and regulatory Feb 11, 2025 · Replacing carbomer and its texture and skin feel is tricky, but doable. April 1, 2022 Sep 22, 2022 · Carbomer, if classified, will be the second most prevalent microplastic used in cosmetic formulations due to its versatility and ease of use. The ability of carbomers and polyvinyl alcohol to cling to the eye surface and their higher viscosity may help reduce frequency of application to 4 times daily. It provides a new generation of rheology modifier with outstanding stability properties. offers a natural alternative to synthetic gelling agents like carbomer. The key to replacing carbomer effectively is defining what function it has in the selected formulation. FDA Recommendations for use of Benzene-Containing Carbomers in Drug Products All Rx and OTC drug products that are formulated to contain Carbomer 934, Carbomer 934P, Carbomer 940, Carbomer 941 or Carbomer 1342 should be immediately reformulated so as to eliminate the use of such carbomers. Carbomer 974P is a carbomer that is the major non-aqueous component (5% polymer, 94% water) of a proprietary formulation called BufferGel, which also contains dibasic potassium phosphate, magnesium sulfate, dibasic sodium phosphate, sorbic acid, monobasic sodium phosphate, and disodium EDTA. Carbopol® 974P NF polymer was introduced for use in oral and mucosal contact applications such as oral liquids, bioadhesive formulations, oral care formulations and extended release tablets. These personal care products contain a specific mixture of carrageenans (including iota, lamda, and kappa carrageenan) and a substituted starch to yield these desired properties. In this webinar, we propose a natural, sustainable and biodegradable alternative to microplastics: Valida. Also, I've noticed lately that after about a day of wear, my hair develops a slight vinegar smell. Plus practical tips on using solubilisers to create clear, aqueous solutions. 2023, the US FDA released guidance on benzene-grade carbomer formulations, which triggered pharmaceutical manufacturers to assess risk, test finished products, and reformulate drug products with benzene-grade carbomer. Apr 1, 2022 · Dear Valerie Making the Right Raw Material Choices for Your Beauty Formulas Some advice on activity levels and thickening with carbomers. , Ph. WebMD's comprehensive database of prescription drug and medication information from A to Z Where an alternative brand of carbomer eye drops is not available, an alternative eye drop should be considered, in line with Grampian Area Formulary. Dec 28, 2023 · However, there are still several grades of carbomers that are manufactured using benzene as a solvent being used in pharmaceutical products even though alternative grades of carbomers are available that are manufactured without the use of benzene. Rather, each option has benefits in certain situations. Carbomers and polyvinyl alcohol are suitable alternatives. The present invention relates to the replacement of carbomer in personal care products with a natural based solution that has a desirable rheology, texture, and viscosity. ALTER-GELIJAC is a natural, plant-based gelling agent that produces translucent, high-viscosity gels. Additionally, Carbopol 974P NF polymer can be used to formulate viscous gels, emulsions and suspensions. Learn more here. Products within the Carbopol® polymer family are chemically similar in that they are all high molecular weight, crosslinked polyacrylic acid polymers. Consultation to fund an alternative carbomer gel eye drop (brand name Viscotears) for people with This article will explore the various carbomer uses in cosmetics, carbomer benefits for skin, address carbomer safety in skincare, and offer insights into carbomer alternatives in skincare. View carbomers information, including dose, uses. It is a derivative of acrylic acid (CH 2 =CHCO 2 H). Jun 18, 2024 · A guide to 4 natural solubilisers for cosmetic formulation. Carbomer is a group of synthetic high molecular weight polymers of acrylic acid used in cosmetics and skincare products as thickening agents. com website. In this guide, we dive into the specifics of “what is Carbomer”, its crucial role in cosmetic formulations, and what you can expect from its use without any fluffy add-ons […] More than a pure alternative to carbomer Outstanding stability This new optimized combination of a biopolymer and a modified starch exhibits exceptional versatility, effectively modifying rheology across a spectrum of low to medium viscosities. Nov 29, 2013 · Expert personal care formulator George Deckner discusses carbomers, including advantages, formulation tips, key suppliers, recommended materials and more. a hydroalcoholic gel hand sanitizer). Please email the communications team: imperial. Understanding the different types of carbomer can also help in selecting products that suit specific skin needs. The texture and skin feel of carbomer make it a difficult product to replace effectively with natural alternatives. The following table shows recommended alternatives for the benzene-grade Carbopol® polymer products based on viscosity criteria. Patients should be directed to self-care. May 31, 2011 · Additionally, it may be desirable to substitute a benzene polymerized carbomer with a non-benzene polymerized carbomer in a pharmaceutical formulation. Made of 100% polysaccharide of natural origin with exceptional gelling and thickening properties, Amigel® is an incomparable stabilizing agent for the formulation of emulsions and suspensions. The carbomer hydrogel has the lowest phase angle (around 5 degrees), meaning it possesses the highest elasticity of all hydrogels. A list of US medications equivalent to Carbomer is available on the Drugs. May 7, 2022 · Amigel® is an alternative to carbomer and other synthetic agents of petrochemical origin. com HEC can be used to make crystal clear serums Aristoflex Eco T is a natural carbomer alternative with an RCI of 71% providing outstanding rheology, oil and particle stabilization and excellent skin feel. Look for the term “carbomer” or its alternative names, such as carbopol or polyacrylic acid, in the ingredient list. Carbomer is a typical ingredient in skincare and cosmetic products that adds texture, thickness, and stability. The tables below summarize the products available, excipients and comparative costs: Basically carbomer is like a bunch of vinegar molecules stuck together. While carbomer resin remains a popular choice for many applications, there is a growing demand for alternatives that are more sustainable, cost-effective, and compliant with regulatory requirements. May 6, 2024 · Most of them produce highly viscous, transparent gels in water at a low use level. Carbomer cannot be replaced by a single natural polymer. See NHS Grampian Guidance for the Management of Dry Eyes for further information. Overall, carbomers are a useful ingredient in hand hygiene products, helping to improve their texture, consistency, and effectiveness. Carbomers and Polyvinyl Alcohol • Products containing carbomers or polyvinyl alcohol are longer acting than hypromellose and may present suitable alternatives if hypromellose does not provide adequate symptom relief. Carbomers Carbomers are acrylic acid polymers that are used for a variety of purposes. Carbomers can be less tolerated than hypromellose due to their impact on vision. 4 days ago · Carbomer is primarily a thickening agent that makes the products more viscous and maintains their texture, flow, and consistency. Carbomer Alternative - Guarsafe® JK-303 s a natural guar-based thickener and film former for hand sanitizer. 4% carbomer is much thicker than a 1. Currently all funded preservative free ocular lubricants (including carbomer, polyethylene glycol 400 and propylene glycol, and sodium hyaluronate [hyaluronic acid]) are subject to the same Special Authority criteria in the community [PDF]. May 14, 2024 · Carbomer 940 is a polyvinyl carboxy polymer used for thickening, gelling, and stabilizing in cosmetics and pharmaceuticals, due to its ability to absorb water, retain moisture, and enhance stability and viscosity of products. Jul 14, 2023 · Carbomers, also known as Rheology Modifiers, are used to optimize cosmetic & pharmaceutical product formulations in profound ways. Jun 15, 2019 · Copolymers and synthetic polymers, like PEGS (polyethylene glycols) and carbomer, are man-made chemicals that are usually used to thicken substances like shampoo or shower gel and when washed down Polyacrylic acid Poly (acrylic acid) (PAA; trade name Carbomer) is a polymer with the formula (CH 2 −CHCO 2 H) n. The immediate implementation of the stoppage of finished products with For more information on directions for use, please refer to the individual product information. The Great Gel Experiment Awhile back, Lisa Lise did a fascinating series of posts experimenting with glucomannan as a plant-based carbomer alternative that inspired me to do some gelling experiments of my own. Feb 6, 2024 · FDA issues guidance on reformulating drug products containing carbomers with benzene to address contamination concerns and ensure pharmaceutical safety. Factors Influencing We would like to show you a description here but the site won’t allow us. We would like to show you a description here but the site won’t allow us. Benzene Free Carbomer: A specialized product formulated without benzene, ensuring a safer alternative for sensitive applications. 0% HEC gel and feels much better on my skin. Oct 24, 2013 · Carbomers, a family of crosslinked acrylic acid polymers, are essential ingredients in numerous products, including: pharmaceuticals; cosmetics and personal care items; household, industrial and institutional care products; printing inks; adhesives and coatings. Ideal to obtain colorless gels with hight viscosities. The purpose of this guidance is to provide recommendations for applicants and manufacturers on what tests should be performed and what documentation should be submitted or available to FDA to support the reformulation of drug products that use carbomers manufactured with benzene Alternative formats This leaflet can be provided on request in large print or easy read, as a sound recording, in Braille or in alternative languages. It is a polymer that is largely utilised in personal care and medicinal products as a thickening, suspending, and emulsifying agent. 3% would be delisted at a later date, once stock was exhausted. Nov 30, 2020 · Tamburic, Slobodanka and Xin Yee, Peh and Baltazar, Diogo (2020) Can Carbomer be effectively replaced with natural polymers? In: 31st IFSCC Congress, Yokohama, Japan, 21-30 Nov 2020, Online. 1–3% (you could use more, but it would be very … Continue reading → Carbomer is a medicine available in a number of countries worldwide. Pricing and pack information for Eye drops and Eye gel forms of Carbomers Dec 27, 2023 · Reformulating Drug Products That Contain Carbomers Manufactured With Benzene Jan 29, 2025 · Rheological Properties: Shear-Thinning Behavior Carbomer gels exhibit a fascinating property called shear-thinning behavior. Our innovative plant-based gelling agent provides exceptional gelling properties similar to carbomer without the use of synthetic chemicals. There is a “translate” button at the top of the page, however, this button is automated and may not be List of alternative rheology modifiers for use in the production of hand sanitizers Many ingredients can be considered as replacements for a rheology modifier used in a clear gel (e. Discover how to replace it in our latest post. D. When the NaOH is added, it reacts with the carbomer (like the volcano experiments) and it swells. In addition to the homopolymers, a variety of copolymers and crosslinked polymers, and partially deprotonated derivatives thereof, are known and of commercial value. This ingredient also absorbs and retains water to make products like Jun 15, 2020 · The natural cosmetics market is growing, in line with the interest of public opinion on environmental safety. However, ocular surface inflammation can be exacerbated by the presence of preservatives such as benzalkonium chloride and evidence suggests that it can destabilise the tear film and also damage the epithelial cells. In Dec. The substitute products are polymerized in either ethyl acetate or a cosolvent mixture of ethyl acetate and cyclohexane. Carbomers are frequently employed in creams, lotions, gels, and other formu Carbomers impart a silky feel to topical pharmaceutical formulations, but they do require neutralisation to do so. Apr 23, 2012 · Konjac glucomannan is examined as a possible plant-based alternative to carbomer May 28, 2023 · Carbomer eye gels relieve eye dryness and soreness. This guide offers detailed insights into Carbomer grades, rheological behavior, and bioadhesive properties, supporting formulators and researchers in product development. They are primarily added to gel-like formulations, such as facial moisturizers, sunscreens, shampoos, anti-aging formulations, cleansers, and Jan 4, 2024 · The guidance defines carbomers as a group of polymers consisting of acrylic acid which are “widely used” as inactive ingredients in drug product fillers, emulsifiers, gelling agents, and binding agents. 2 billionForecast (2033): USD 2. They are used in pharmaceutical processes as suspending agents, gel bases, emulsifiers, and binding agents. Mar 18, 2024 · Carbomer is a key ingredient in many personal care products, serving as a thickener and stabilizer to enhance the texture of creams, gels, and lotions. For transparency, gums like Cellulose or Xanthan work well for clarity while Guar or Tara gum shine in more opaque formulations achieving higher viscosities. In this article, George Deckner explains the science behind thickeners and offers product recommendations for best water-based thickeners. 3 days ago · The Carbomer for Facial Care Market is a vital segment within the broader cosmetics and skincare industry, primarily focusing on the utilization of carbomer-based thickeners, stabilizers, and Doesn't seem to give as much volume as HEC or carbomer, but this might be the because of the increased definition. Oct 14, 2024 · In September 2024, Pharmac consulted on a proposal to fund an alternative carbomer gel eye drop (brand name Viscotears) for people with dry eyes. If have any queries relating to this information, please contact the Ophthalmology service Alternative formats You can use the accessibility toolbar at the bottom of your screen to change the text size and colour contrast on this page. The DEWS3 report (peer reviewed guidance which is the accepted main reference source) concluded there is no evidence to suggest that any one agent is superior to another. The most widely used is carbomer 940, whose efficacy and good tolerance in the treatment of dry eyes has been established?-ll Viscotears (marketed as Viscotears in Switzerland and the United The main advantage of carbomer over other thickeners like xanthan gum and cellulose derivatives is that it can form very viscous gels at very low concentrations and give a clean feel with no stickiness at all. ALTER-GELIJAC Gelling agent Description of the item A gelling agent allowing high viscosity, plant alternative to carbomer. It is used, for example, as an emulsifier and thickener in personal care products, to make medical implants, as a superabsorber in self-healing concrete and as a binder in a coating formulation for paper. Refer to secondary care if symptoms persist, do not respond to 3 different drops for 4-6 weeks each or vision deteriorates – see Prescribing Guidance for more detail. This swelling traps water, making the jelly. Not every carbomer can take so much alcohol, you will need to check how much they can carry, especially with so low percentage of water. This column will explore the chemistry and properties of carbomers that have earned them this well-deserved reputation. They are also used as artificial tears. Oct 29, 2021 · Polyacrylic acid (also known as Carbomer) is a versatile polymer. g. Natural ‘gelling’ agent(s) should be combined with ‘thickening’ agent(s) to increase the mechanical strength of the network. Acrylates Crosspolymer: A versatile polymer used in various formulations, providing superior texture and stability. Some carbomers currently used as inactive ingredients are manufactured with benzene as a polymerization solvent. Apr 20, 2018 · The best thickener to use in a formulation is the most efficient one. These monographs allow benzene levels as high as 5,000 parts per million (ppm). The analysis of Figure 2 shows that both carbomer hydrogel (open pink circle) and the corresponding emulsion (closed pink circle) take distinct places in the plot, quite away from other hydrogels and emulsions. It is a perfect alternative to synthetic polymers. Mar 5, 2024 · These diverse synthetic alternatives to Carbomer offer varied thickening properties and stability, catering to the varied needs of skincare formulations. It is used in numerous products such as lotions, shampoos, lipsticks, nail polishes, etc. This study focused on replacing carbomers using combinations of natural polymers of the polysaccharide type. The availability of polysaccharides for cosmetic use is very wide; each raw material has its own sensorial specificities and hardly matches the performance of synthetic polymers. Once the shear stress is removed, the viscosity recovers, and the gel retains its structure. For example, the recipe below with 0. Dec 22, 2023 · Carbomers are synthetic polymers of acrylic acid, which manufacturers include in many products, including cosmetics. Carbomer 974P is a carbomer that is the major non-aqueous component (5% polymer, 94% water) of a proprietary formulation called BufferGel, which also contains Natural Gelling Agents: Eco-Friendly Alternatives to Carbomer from China Supplier Tianjin YR ChemSpec Technology Co. Learn more about side effects at Patient. The History of Carbomers – Trusted Safe – Proven Over Time The safety profiles of Carbomers are attested by their extensive history of safe use in cosmetics and pharmaceuticals. It is anticipated that the revenue will experience a compound annual growth rate (CAGR 2025-2031) of 3 days ago · 📥 Download Sample 💰 Get Special Discount Malaysia Carbomer for Pharmaceutical Market Size, Strategic Outlook & Forecast 2026-2033Market size (2024): USD 1. Aug 4, 2025 · These effective alternatives have inspired our ready-to-use natural thickeners, that deliver high viscosity and great sensory feel, without compromising on performance or the planet. In simpler terms, the gel becomes thinner when you rub it, making it easy to spread and apply. net We would like to show you a description here but the site won’t allow us. Learn more. INCI Hydroxyethylcellulose Appearance Fine off-white powder Usage rate 0. , Ltd. Apr 15, 2009 · Published April 15, 2009 Which Drop for Dry Eye? When it comes to treating dry eye, keep your armamentarium well stocked. It is ideal for thickening solutions containing high ethanol content. Sepimax Zen & Carbomer Natural Alternative & Substitute Learn Organic Cosmetics Formulation With Stable Formulas - https://naturalskincareschool. No single artificial tear works well for every form of dry eye. Simple dry eye is an uncomplicated condition which can be managed without medical intervention. Srihari Narayanan, O. Sensory testing can not be completely replaced by instruments; the two methods should be combined. Jan 11, 2024 · According to the FDA, carbomers manufactured with benzene that are used in FDA-regulated drug products may fall under the United States Pharmacopeia-National Formulary (USP-NF) monographs Carbomer 934, Carbomer 934P, Carbomer 940, Carbomer 941, or Carbomer 1342. The present invention also relates to a blend 1 day ago · Los Angeles, USA - Carbomer for Hair Care market is estimated to reach USD xx Billion by 2024. Nov 13, 2022 · What Is Carbomer? Carbomer is the commonly used name for an ingredient called polyacrylic acid (PAA). Therefore, we hypothesized that agarose stearate–carbomer 940 (AS/CBM 940) combination system might have the possibility of replacing, partially or completely, the surfactants in the cosmetic formulation, while maintaining a long-term stability and the characteristic rheological and organoleptic properties of the cosmetics. Indications, side effects, contraindications and other prescribing information for Dry eye drugs on MIMS Explore a comprehensive scientific overview of Carbomer-its molecular structure, thickening mechanisms, pharmaceutical and cosmetic applications, and advanced roles in materials science. Download scientific diagram | Different grades of carbomers and their properties from publication: Comprehensive review of the role of acrylic acid derivative polymers in floating drug delivery Additionally, it may be desirable to substitute a benzene polymerized carbomer with a non-benzene polymerized carbomer in a pharmaceutical formulation. They are high molecular weight polymers derived from the crosslinking of the polyacrylic acid. However, growing competition as a result of globalization is forcing many manufacturers to explore alternative carbomers to minimize production costs and potentially compromise on quality performance. Oct 28, 2025 · Conclusion As a carbomer resin supplier, I understand the importance of providing our customers with high-quality products and solutions.

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